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descriptionBiochemistry II (Cliffs Quick Review)

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Frank Schmidt - Biochemistry II (Cliffs Quick Review)
Published: 2000-07-24 | ISBN: 0764585622 | PDF | 80 pages | 3 MB

We take great notes — and make studying a snap When it comes to
pinpointing the stuff you really need to know, nobody does it better
than CliffsNotes. This fast, effective tutorial helps you master the
core concepts of Biochemistry II — and get the best possible grade. From
biosynthesis and integrated metabolism to the molecular cloning of DNA,
you get clear, jargon-free explanations of all the fundamentals,
illustrated throughout with a wealth of formulas and figures. Study
smarter @ cliffsnotes.com Free test-taking tips and tricks Free test
samples and schedules Free info on other test resources Free
CliffsNote-A-Day™ tips Plus hundreds of downloadable Cliffs titles 24
hours a day Make the grade with CliffsQuickReviews CliffsQuickReviews
are available for more than 30 introductory level courses. See inside
for a complete listing of these and other bestselling Cliffs titles.

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descriptionRe: Biochemistry II (Cliffs Quick Review)

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Although database search identification of proteins by mass  spectrometry is well established, the method does not apply if the protein  sequence does not exist in the current database. Therefore, de novo sequencing is  the only method for identifying novel peptides, unsequenced organisms, and antibodies  drugs, which database search methods were not able to detect. However, de novo  sequencing poses more challenging than the traditional database search  approach, such as, ambiguous assignments of fragment ions, insufficient product  ions generated in incomplete fragmentation leading to low sequence coverage and  difficulty in distinguishing ion series, notable N-terminal from C-terminal  MS/MS product ions (b ions from y ions).
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